General Information

Product

TPCN2 Antibody

Description

Affinity Purified Two pore calcium channel protein 2 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 680-731.

Accession #

NCBI: NP_666318.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.57 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q8BWC0

Overview

Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the major voltage-gated Ca2+ channels (VDCC) across the lysosomal membrane. May be involved in smooth muscle contraction.

Molecular Function

Calcium channel, Ion channel, Voltage-gated channel

Subcellular Location

Lysosome membrane; Multi-pass membrane protein

Expression

Widely expressed. Expressed at high level in liver and kidney.

Structure

Homodimer. Interacts with LRRK2.

Alternative Nomenclature

SHEP10 antibody

TPC2 antibody

Two pore calcium channel protein 2 antibody

Voltage dependent calcium channel protein TPC2 antibody