General Information

Product

Myosin 1C Antibody

Description

Affinity Purified Unconventional Myosin-Ic / Myo 1C Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse

Immunogen

Synthetic peptide taken within amino acid region 1-50 on mouse Unconventional Myosin-Ic / Myo 1C.

Accession #

NCBI: NM_001080775

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:2,500-1:5,000

Protein

Uniprot #

Q9WTI7

Overview

actin binding

actin-dependent ATPase activity

actin filament binding

ATP binding

calmodulin binding

microfilament motor activity

phospholipid binding

protein C-terminus binding

Ral GTPase binding

signaling receptor binding

Molecular Function

Cell membrane, Cytoplasm

Expression

Binds directly to large unilamellar vesicles (LUVs) containing phosphatidylinositol 4,5-bisphosphate (PIP2) or inositol 1,4,5-trisphosphate (InsP3). The PIP2-binding site corresponds to the myosin tail domain (PH-like) present in its tail domain.

Structure

Unconventional Myosin-Ic / Myo 1C

Alternative Nomenclature

MMI beta antibody

MMIb antibody

MYO1C antibody

Myosin I beta antibody

Myosin-Ic antibody

MYR2 antibody

NMI antibody

Nuclear myosin I antibody