Synthetic peptide corresponding to region within amino acids 1-50 on N-terminus of human PDE2A3 protein.
Specificity
This antibody will detect PDE2A3 only.
Accession #
NCBI: NP_002590.1
Physical Properties
Quantity
100 µg
Volume
200 µl
Concentration
0.5 µg/µl in antibody stabilization buffer
Immunoglobulin
IgG
Form
Affinity Purified
Clonality
Polyclonal
Determinant
N-epitope
Storage
-20⁰C for long term storage
Application Protocol
ELISA
1:10,000
Immunohistochemistry
1:100
Immunoprecipitation
1:200
Western Blot
1:500
Protein
Uniprot #
O00408
Overview
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.
Molecular Function
Calcium channel activity, cAMP binding, cGMP binding, cGMP-stimulated cyclic-nucleotide phosphodiesterase activity; drug binding; metal ion binding; protein homodimerization activity; TPR domain binding
Subcellular Location
Cell membrane; Lipid-anchor
Expression
Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas.
Structure
Belongs to the cyclic nucleotide phosphodiesterase family. PDE2 subfamily.
Contains 2 GAF domains.
Alternative Nomenclature
Phosphodiesterase 2A 3
Protein information supplied by UniProt
To view the Specification Sheet for PDE2A3 Antibody, please click the link below: