General Information

Product

Cannabinoid Receptor II Antibody

Description

Affinity Purified Cannabinoid receptor 2 Antibody

Verified Applications

ELISA, IHC, IP,WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 300-350 on mouse CB2 Receptor protein common to both CB2L and CB2S.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.61-0.63 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DOT Blot

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P47936

Overview

Heterotrimeric GPCR for endocannabinoid 2-arachidonoylglycerol mediating inhibition of Adenylate cyclase. Functions in inflammatory response, nociceptive transmission and bone homeostasis.

Molecular Function

Inflammatory response; GPCR; Receptor; Transducer

Subcellular Location

Cell membrane; Multi-pass membrane protein; Dendrite; Perikaryon

Expression

Cells of hematopoietic origin. Expressed in skin in suprabasal layers and hair follices. In brain by neurons and glial cells. Expressed in osteoblasts, osteocytes and osteoclasts.

Structure

belongs to G-protein coupled receptor 1 family

Alternative Nomenclature

Cannabinoid receptor 2 macrophage antibody

CB 2 antibody

CNR2 antibody

CX 5 antibody

testis-dominant CNR2 isoform CB2 antibody