General Information

Product

EDG8 Antibody

Description

Affinity Purified Sphingosine 1-phosphate receptor 5 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 380-400ofrat S1P5R/EDG8protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.52-0.63 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9JKM5

Overview

Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/O)alpha and G(12) subclass of heteromeric G-proteins.

Molecular Function

G-protein coupled receptor, Receptor, Transducer

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Found almost exclusively in brain and skin. Ubiquitously detected in different brain regions with very prominent expression in lower brain regions such as the midbrain, pons, medulla, and spinal cord. Expressed predominantly within white matter tracts of

Alternative Nomenclature

EDG 8 antibody

Endothelial differentiation G protein coupled receptor 8 antibody

Endothelial differentiation sphingolipid G protein coupled receptor 8 antibody

S1P receptor 5 antibody

S1P receptor Edg 8 antibody

Sphingosine 1 Phosphate Receptor 5 antibody

Sphingosine 1-phosphate receptor Edg-8 antibody

SPPR2 antibody