General Information

Product

Aquaporin 8 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Sheep, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 215-263 on rat Aquaporin 8 protein.

Accession #

GenBank: BAA21918

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50-0.95 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P56405

Overview

Forms water specific channel. Mercury-sensitive. Plays role in spermatogenesis, fertilization, and in secretion of pancreatic juice and saliva.

Molecular Function

Transport

Subcellular Location

Membrane; Multi-pass protein

Expression

Sperm, pancreas and liver. Less expressed in salivary gland and absoptive colonic epithelial cells.

Structure

Contain two tandem repeats each with three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala

Alternative Nomenclature

AQP8 antibody

Aquaporin 8 antibody